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The Tong Lab in the Department of Biological Sciences is seeking an Associate Research Scientist. The incumbent should have a full set of experimental skills with structural biology, including protein expression and purification in bacteria and insect cells, protein crystallization, X-ray diffraction data collection and processing, crystal structure determination and refinement, cryo-EM grid preparation and screening, cryo-EM data analysis, cryo-EM model building and refinement, structural analyses and mutagenesis studies.
The responsibilities of this position will include:
· Cryo-EM studies of proteins involved in RNA decapping and possibly other biochemical processes.
· Crystallographic studies of proteins involved in RNA decapping in plants and other organisms.
· Detailed analyses of the structures that are obtained, and design mutagenesis experiments to assess the structural observations.
· Working closely with collaborators, within Columbia and also with other institutions, on multi-faceted projects.
· Preparing reports for grant submissions and drafting manuscripts detailing the results of studies for publication.
· Mentoring PhD students and colleagues on related projects.
Minimum Degree Required: PhD
Field(s) of Specialization: Molecular Biology and Biochemistry
All applications must be made through Columbia University?s online Academic Search and Recruitment System (ASR). On the site, please upload cover letter, CV, and a list of reference providers (who may be asked to provide a letter at a later date).
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Pay Transparency Disclosure
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University?s good faith and reasonable estimate of the range of possible compensation at the time of posting.
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.